Medicines Formulary

Medicines A–Z

L

Drug name	NICE TAs	Comments
Lansoprazole
Lansoprazole orodispersible tablets		Second line - for use in swallowing difficulties or via nasogastric tubes.
Lanthanum tablets		Specialist recommendation.
Lapatinib tablets	TA257 - Lapatinib or trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone-receptor-positive breast cancer that overexpresses HER2	Negative TA
L-arginine capsules
L-arginine infusion (100ml)
L-arginine oral solution
L-arginine tablets
Laronidase infusion (Aldurazyme)
Larotrectinib (Vitrakvi®)	TA630 - Larotrectinib for treating NTRK fusion-positive solid tumours

Drug status key

Formulary drugs are allocated a traffic light status. This provides guidance on where clinical and prescribing responsibilities lie in regard to the initiation and maintenance of prescribing.

Grey

Positive NICE TA and/or awaiting local clarification on place in therapy. Please contact your medicines optimisation team for more information.

Red

Initiation and maintenance of prescribing by specialists only.

Amber

Initiation and maintenance of prescribing by specialists and transfer to primary care prescribing when appropriate, or in primary care following a specialists recommendation. Prior to initiation some medicines may require committee agreement or a framework to support safe transfer and maintenance.

Green

Initiation and maintenance of prescribing by specialists, GPs and other qualified clinicians.

Blue

Under review at University Hospitals Birmingham NHS Foundation Trust.