Medicines Formulary

Medicines A–Z

L

Drug name	NICE TAs	Comments
Lorazepam
Lorazepam injection
Lorazepam tablets
Lorlatinib (Lorviqua®)	TA628 - Lorlatinib for previously treated ALK-positive advanced non-small-cell lung cancer
L-ornithine L-aspartate 5gm/10ml injection
Losartan tablets
Loteprednol etabonate 0.5% eye drops
Lotriderm® cream		Potent
Lumacaftor-ivacaftor (Orkambi®)	TA398 - Lumacaftor-ivacaftor for treating cystic fibrosis homozygous for the F508del mutation	NHSE commissioning statement
Lusutrombopag (Mulpleo®)	TA617 - Lusutrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure

Drug status key

Formulary drugs are allocated a traffic light status. This provides guidance on where clinical and prescribing responsibilities lie in regard to the initiation and maintenance of prescribing.

Grey

Positive NICE TA and/or awaiting local clarification on place in therapy. Please contact your medicines optimisation team for more information.

Red

Initiation and maintenance of prescribing by specialists only.

Amber

Initiation and maintenance of prescribing by specialists and transfer to primary care prescribing when appropriate, or in primary care following a specialists recommendation. Prior to initiation some medicines may require committee agreement or a framework to support safe transfer and maintenance.

Green

Initiation and maintenance of prescribing by specialists, GPs and other qualified clinicians.

Blue

Under review at University Hospitals Birmingham NHS Foundation Trust.